(One student per topic. Type name into box and click on Confirm.)
1. Diseases caused by the abnormalities of adenosine deaminase: a structural interpretation
Evelyn Kono
2. Structure-based design of HIV protease inhibitors
Andrew Pomfret
3. Structural bases of plasminogen activation
Ge Zhou
4. Light driven proton pumping by bacteriorhodopsin
Sarah Benson
5. Atomic model for actin filaments decorated with myosin S1
thomas topini
6. Atomic structure of microtubule filaments
Alberto
7. Regulation of actin by tropomyosin
Elisa Bergamin
8. Substrate specificity of water and glycerol channels (AQP-1 and GlpF)
Alberto
9. Mechanism of ATP hydrolysis-coupled substrate translocation across the membrane by ATP-Binding Cassette (ABC) transporters
Jon Lefman
10. The energy conversion mechanism of cytochrome reductase (Complex III)
Yuan Shirley Li
11. Structural basis for activation of tumor necrosis factor (TNF) receptor
Sheng Ge
12. Structural requirements for erythropoietin (Epo) receptor activation
Abby Deans
13. Mechanism of EGF receptor activation
Rafael Depetris
14. Inhibition of c-Abl and c-Kit by STI-571
Janelle Waite
15. Role of RGS proteins in GTP hydrolysis by G alpha proteins
kwame
16. Phosphothreonine recognition by forkhead-associated (FHA) domains
Jonathan Scheiman
17. Structure and mechanism of DNA topoisomerases
Ilana Gimpelevich
18. Structure, specificity, and mechanism of archaeal and eukaryotic tRNA splicing endonucleases
Diego Acosta
19. Mechanism and tRNA substrate specificity of the E. coli and yeast aspartyl-tRNA synthetases
Catherine Potenski
20. Structural basis of ion selectivity of the CIC chloride channel
Jeffrey Savas
21. Structural basis of the thrombin and platelet glycoprotein Ib_alpha interaction and its implication in blood clotting
Kimberly O'Malley
22. Functional role of heterogeneous fatty acylation of proteins
Thomas Topini
23. Redesigning the ATP-binding site of protein kinases to identify specific cellular substrates
David Khoo
24. Structural basis for Eph/ephrin signaling
Daniel Spellman
25. Brownian Ratchet Mechanisms for Biological Macromolecule
Will Findley