Week 5 - Molecular machines

Instructor:
David Stokes
Skirball 3-13
x3-1580
stokes@saturn.med.nyu.edu

Class locations:
Mon:  Skirball 3rd floor seminar room
Wed:  Skirball 3rd floor seminar room
Fri:  Skirball 3rd floor conference room

Reading assignment:

For Monday, Oct 13:
textbook:
pgs. 191-194 (leucine zipper)
pgs. 251-260 (G proteins)
pgs. 290-298 (myosin)
Geeves, M.A. & K.C. Holmes. 1999. Structural Mechanism of Muscle Contraction. Annu. Rev. Biochem. 68:687-728 (pgs. 687-718 most relevant for us)
Vale & Milligan. 2000. Science 288:88-95
(sorry, I changed my mind about this reference)

For Wednesday, Oct 15:

Oster, G. & H. Wang. 1999. ATP synthase: two motors, two fuels. Structure 7:R67-R72.

Stokes & Green. 2003. Annu Rev Biophys Biomol Struct. 32:445-68.
This contains far too much detail - you won't want to read the whole thing.

Discussion paper: Taylor et al. 1999. Cell 99:421-431

Lectures:

Myosin and Kinesin

FoF1 and Ca-ATPase

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