Week 1: Principles of protein structure and folding

Instructors:
Steve Hubbard
Skirball 3-4
x3-8938
hubbard@saturn.med.nyu.edu

Neville Kallenbach
Chemistry Dept.
1170 Waverly Building
998-8757
neville.kallenbach@nyu.edu

Class locations:
Mon:  Skirball 5th floor conference room
Wed:  Skirball 3rd floor seminar room
Fri:  Skirball 3rd floor conference room

Reading assignment:
Branden and Tooze: Chapters 1, 2 and 6 (pp. 89-105).
Daggett, V. and Fersht, A., "The present view of the mechanism of protein folding", Nat. Rev. Mol. Cell Biol. 4, 497-502 (2003).

Discussion paper:
Pauling, L., Corey, R.B., and Branson, H.R., "The structure of proteins: two hydrogen-bonded helical configurations of the polypeptide chain", Proc. Natl. Acad. U.S.A. 37, 205-211 (1951).

Lectures:
Principles of Protein Structure (pdf)

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