2009 - Structure of the Synapse

Structure of the Synapse

Friday, June 05, 2009
9:30 AM - 5:00 PM Farkas Auditorium
New York University School of Medicine,
540 First Ave., New York, NY

The 2009 Skirball Symposium is open to the public, with no registration fee.
Feel free to spread the word!

We are our synapses. A synapse is the site where neurons meet and communicate with each other. It is also the place where defects in architecture or communication cause diseases like Alzheimer's and Parkinson's. Most drugs known to affect the brain exert their therapeutic effects at the synapse. Therefore, studying synaptic architecture and transmission mechanism is crucial for an understanding of physiologic processes - learning and memory - and disease pathogenesis. In recent years, great progress has been made in identifying the major components of the synapse and their interplay: vesicle fusion proteins, scaffolding proteins, neurotransmitter transporters, receptors and channels. The 2009 Skirball Symposium, "Structure of the Synapse," will bring together some of the world's leading experts in this field to review the most recent breakthroughs in synaptic structure and mechanism, and how such work will impact the clinical disciplines of neurology, psychiatry and neuropharmacology.


09:30AM Introduction
Dr. Ruth Lehmann, Director, Skirball Institute, NYU School of Medicine
09:45AM Overview
Chuck Stevens, Salk Institute
10:30AM Synaptic vesicles
Reinhard Jahn, Max-Planck Institute
11:15AM Coffee Break
11:35AM Vesicle fusion
Axel Brunger, Stanford University / HHMI
12:20PM Neurotransmitter transporters and receptors
Eric Gouaux, Vollum Institute / HHMI
1:15PM Lunch
2:45PM Neurotransmitter-gated ion channels
Nigel Unwin, MRC Laboratory of Molecaular Biology
3:30PM Post-synaptic density
Morgan Sheng, MIT HHMI
4:15PM Diseases
Robert Malenka, Staford University
5:00PM Closing - Dr. Ruth Lehmann, Skirball Institute

The 2009 Skirball Institute Eleventh Annual Symposium is organized by Da-Neng Wang and Stevan Hubbard.

Direct all inquiries to Laura Rivera.