2008 - Inflammation and Host Defense

Inflammation and Host Defense

Friday, November 21, 2008
9:30 AM - 5:00 PM Farkas Auditorium
New York University School of Medicine,
540 First Ave., New York, NY

The 2008 Skirball Symposium is open to the public, with no registration fee.
Feel free to spread the word!

While it has been recognized for more than a century that the generation of an inflammatory response is critical for controlling invading pathogens, recent studies have shown that defective regulation of various branches of the immune system contributes not only to autoimmune diseases such as rheumatoid arthritis, type I diabetes, multiple sclerosis, psoriasis, lupus, and Crohn's disease, but also to other diseases of great public health relevance, such as asthma and several whose connection to the immune system and inflammation is only now being appreciated. Most prominent among these are atherosclerotic disease, type II diabetes, various cancers, and possibly Alzheimer's disease. In addition, strong immune responses to some viruses, such as SARS, influenza, RSV, and the hepatitis viruses can inflict more damage than the viruses themselves. The 2008 Skirball Symposium "Inflammation and Host Defense" will explore the latest understanding of how the immune system is regulated during health, the mechanisms whereby the immune system is aberrantly activated in disease, and how knowledge of these mechanisms is being exploited for the discovery of new classes of drugs for common diseases.

Preliminary Program

09:30AM Introduction
Dr. Ruth Lehmann, Director, Skirball Institute, NYU School of Medicine
09:45AM Nod-like Receptors in Innate Immunity and Disease
Dr. Gabriel Nuñez, University of Michigan
10:30AM Inflammatory Basis of Metabolic Diseases
Dr. Gökhan Hotamisligil, Harvard University
11:15AM Coffee Break
11:35AM Tracking Allergic Immunity
Dr. Richard Locksley, University of California at San Francisco
12:20PM Inflammation and Immune Mechanisms in Atherosclerosis
Dr. Goran Hansson, Karolinska University Hospital
1:15PM Lunch
2:45PM Gut reactions: Immune Regulation in the Intestine in Health and Disease
Dr. Fiona Powrie, University of Oxford
3:30PM Tissue-Specific Mechanisms Regulating Inflammation-Associated Epithelial Carcinogenesis
Dr. Lisa Coussens, University of California at San Francisco
4:15PM Helping the Immune System Regulate Itself
Dr. Hermann Waldmann, University of Oxford
5:00PM Closing - Dr. Ruth Lehmann, Skirball Institute