2015 Symposium - The Dynamic Nucleus


2015 Symposium - The Dynamic Nucleus

The Dynamic Nucleus - Also known as the heart of the cell, the nucleus is the repository for genetic information that supplies information to the entire cell. A distinguished list of speakers will cover the dynamic view of nuclear biology, which has witnessed a revolution in our understanding of coding sequence, regulatory elements, epigenetic modifiers, and spatial and temporal organization. They will also focus on the dynamic interplay between key nuclear regulators and its impact on cellular and organismal function.


Friday, September 18, 2015

9:30 AM - 6:00 PM Farkas Auditorium

NYU Langone Medical Center
550 First Ave., New York, NY

The 2015 Skirball Symposium is open to the public. Registration is not required.



8:30 AM

Continental Breakfast - Outside Farkas Audiotorium

9:30 AM

Welcome and Introduction
Ruth Lehmann, PhD, Director, The Skirball Institute

9:40 AM

Chromosome structure and transcriptional control in normal cells and in cancer 
Ochoa Lecture *
Richard (Rick) Young, PhD - Whitehead Institute for Biomedical Research

10:25 AM

Mutagenesis from defects in nuclear organization and integrity
David Pellman, MD - Children's Hospital Boston and Harvard Medical School; HHMI

11:10 AM

Coffee Break - Outside Farkas Audiotorium

11:30 AM

Towards a Human Cell Atlas
Aviv Regev, PhD - Broad Institute of MIT and Harvard; HHMI 

12:15 AM

The permeability barrier of nuclear pore complexes
Dirk Görlich, PhD - Max Planck Institute for Biophysical Chemistry

1:00 PM

Lunch Break

2:30 PM

Programming biological operating systems: genome design, assembly and activation
Daniel Gibson, PhD - J. Craig Venter Institute

3:15 PM

Epigenetic Dynamics of X-Chromosome inactivation
Edith Heard, PhD, FRS - Institut Curie/College de France

4:00 PM

Break - Refreshments outside of Farkas Audiotorium

4:30 PM

Molecular Functions of PARP family members in transcription and activation and DNA repair
Karolin Luger, PhD - Colorado State University, HHMI

5:15 PM

Monitoring Translation in Space and Time with Ribosome Profiling
Jonathan Weissman, PhD - Univeristy of California, San Francisco; HHMI

6:00 PM

Ruth Lehmann, PhD, Director, The Skirball Institute

* The Severo Ochoa lectureship was established by Drs. Bernard Levine and Joseph Schlessinger in 1998 to honor Severo Ochoa, Chairman of the Department of Pharmacology and then of Biochemistry at New York University School of Medicine. Dr. Ochoa shared the 1959 Nobel Prize in Physiology or Medicine with Arthur Kornberg of Stanford University for unraveling the mechanisms of the biological synthesis of ribonucleic acid and deoxyribonucleic acid.

The 2015 Skirball Institute 16th Annual Symposium is organized by Karim-Jean Armache, Moses Chao, Agnel Sfeir, Susan Smith, Matthias Stadtfeld, and Mamta Tahiliani

Direct all inquiries to Laura E. Rivera 212-263-3289