Cadwell Lab Publications

  1. Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine.
    Cadwell K, Patel KK, Maloney NS, Liu TC, Ng AC, Storer CE, Head RD, Xavier R, Stappenbeck TS, Virgin HW.
    Cell. 2010 Jun 25;141(7):1135-45.
  2. Role of autophagy and autophagy genes in inflammatory bowel disease.
    Cadwell K, Stappenbeck TS, Virgin HW.
    Curr Top Microbiol Immunol. 2009;335:141-67.
  3. Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters.
    Ju JS, Miller SE, Jackson E, Cadwell K, Piwnica-Worms D, Weihl CC.
    Autophagy. 2009 May;5(4):511-9.
  4. Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes.
    Stephenson LM, Miller BC, Ng A, Eisenberg J, Zhao Z, Cadwell K, Graham DB, Mizushima NN, Xavier R, Virgin HW, Swat W.
    Autophagy. 2009 Jul;5(5):625-35.
  5. A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease.
    Cadwell K, Patel KK, Komatsu M, Virgin HW 4th, Stappenbeck TS.
    Autophagy. 2009 Feb;5(2):250-2.
  6. Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens.
    Zhao Z, Fux B, Goodwin M, Dunay IR, Strong D, Miller BC, Cadwell K, Delgado MA, Ponpuak M, Green KG, Schmidt RE, Mizushima N, Deretic V, Sibley LD, Virgin HW.
    Cell Host Microbe. 2008 Nov 13;4(5):458-69.
  7. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells.
    Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, Lennerz JK, Kishi C, Kc W, Carrero JA, Hunt S, Stone CD, Brunt EM, Xavier RJ, Sleckman BP, Li E, Mizushima N, Stappenbeck TS, Virgin HW 4th.
    Nature. 2008 Nov 13;456(7219):259-63.
  8. The specificities of Kaposi's sarcoma-associated herpesvirus-encoded E3 ubiquitin ligases are determined by the positions of lysine or cysteine residues within the intracytoplasmic domains of their targets.
    Cadwell K, Coscoy L.
    J Virol. 2008 Apr;82(8):4184-9.
  9. The autophagy gene ATG5 plays an essential role in B lymphocyte development.
    Miller BC, Zhao Z, Stephenson LM, Cadwell K, Pua HH, Lee HK, Mizushima NN, Iwasaki A, He YW, Swat W, Virgin HW 4th.
    Autophagy. 2008 Apr 1;4(3):309-14.
  10. Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase.
    Cadwell K, Coscoy L.
    Science. 2005 Jul 1;309(5731):127-30.