Juan J. Lafaille

Professor, Skirball Institute of Biomolecular Medicine, Molecular Pathogenesis. Departments of Pathology and Medicine

Ph.D., 1988, University of Sao Paulo, Brazil




Contact Information: 

Skirball Institute of Biomolecular Medicine
540 First Avenue 2nd floor, Lab 7
New York, N.Y. 10016
Office Tel: (212) 263-1489
Lab Tel: (212) 263-1469
Fax: (212) 263-5711
E-mail: juan.lafaille@med.nyu.edu

Administrative Contact:

Richard Stout
Tel: (212)263-6282
Email: richard.stout@med.nyu.edu

Pathogenesis of Autoimmune and Allergic Diseases





Selected Publications:

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells. Weiss JM, Bilate AM, Gobert M, Ding Y, Curotto de Lafaille MA, Parkhurst CN, Xiong H, Dolpady J, Frey AB, Ruocco MG, Yang Y, Floess S, Huehn J, Oh S, Li MO, Niec RE, Rudensky AY, Dustin ML, Littman DR, Lafaille JJ. J Exp Med. 2012 Sep 24;209(10):1723-42. Epub 2012 Sep 10. PMID: 22966001

Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function. Zanin-Zhorov A, Lin J, Scher J, Kumari S, Blair D, Hippen KL, Blazar BR, Abramson SB, Lafaille JJ, Dustin ML. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1625-30. Epub 2012 Jan 17. PMID: 22307621

Sequential class switching is required for the generation of high affinity IgE antibodies. Xiong H, Dolpady J, Wabl M, Curotto de Lafaille MA, Lafaille JJ. J Exp Med. 2012 Feb 13;209(2):353-64. Epub 2012 Jan 16. PMID: 22249450

Induced CD4+Foxp3+ regulatory T cells in immune tolerance. Bilate AM, Lafaille JJ. Annu Rev Immunol. 2012;30:733-58. Epub 2012 Jan 6. Review. PMID: 22224762

Lipid phosphate phosphatase 3 enables efficient thymic egress. Bréart B, Ramos-Perez WD, Mendoza A, Salous AK, Gobert M, Huang Y, Adams RH, Lafaille JJ, Escalante-Alcalde D, Morris AJ, Schwab SR. J Exp Med. 2011 Jun 6;208(6):1267-78. Epub 2011 May 16. PMID: 21576386

Click here to see all publications in PubMed