Jesús Torres-Vázquez

Associate Professor, Skirball Institute of Biomolecular Medicine, Developmental Genetics. Department of Cell Biology

Ph.D., 2001, University of California, Irvine

LAB WEBSITE:
Torres-Vázquez Lab
KEYWORDS:
Vasculature, Angiogenesis, Endothelial, Morphogenesis, Zebrafish, Barriegenesis

Contact Information

Skirball Institute of Biomolecular Medicine
540 First Avenue 4th floor, Lab 14
New York, N.Y. 10016
Office Tel: (212) 263-0259
Lab Tel: (212) 263-0298
Fax: (212) 263-7760
E-mail: jesus.torres-vazquez@med.nyu.edu

Admin Contact

Eileen Cordero
Tel: (646) 501-0679
Email: eileen.cordero@med.nyu.edu


Regulation of vascular development and function

We use the zebrafish and cultured endothelial cells as complementary model systems to understand the cellular behaviors and genetic programs that regulate the formation and function of the vascular tree.

                
 

Key areas of interest in the lab include:

Molecular control of the anatomical patterning of the vasculature

Organ-specific vascularization (cerebral angiogenesis and barriergenesis)

Selected Publications: 
  • Florian Ulrich, Jorge Carretero-Ortega, Javier Menéndez, Carlos Narvaez, Belinda Sun, Eva Lancaster, Valerie Pershad, Sean Trzaska, Evelyn Véliz, Makoto Kamei, Andrew Prendergast, Kameha R. Kidd, Kenna M. Shaw, Daniel A. Castranova, Van N. Pham, Brigid D. Lo, Benjamin L. Martin, David W. Raible, Brant M. Weinstein, Jesús Torres-Vázquez (2015). Reck enables cerebrovascular development by promoting canonical Wnt signaling. Development (doi: 10.1242/dev.123059). PMID: 26657775
  • Zygmunt T, Trzaska S, Edelstein L, Walls J, Rajamani S, Gale N, Daroles L, Ramírez C, Ulrich F, Torres-Vázquez J. (2012). In parallel interconnectivity of the dorsal longitudinal anastomotic vessels requires both VEGF signaling and circulatory flow. J Cell Sci. Aug 16. PMID: 22899709
  • Tomasz Zygmunt; Carl M Gay; Jordan Blondelle; Manvendra K Singh, Kathleen M Flaherty; Paula C Means; Lukas Herwig; Alice Krudewig; Heinz-Georg Belting; Markus Affolter; Jonathan A Epstein and Jesús Torres-Vázquez. (2011). Semaphorin-PlexinD1 Signaling Limits Angiogenic Potential via the VEGF Decoy Receptor sFlt1. Developmental Cell 21 (2), 301-14. PMID: 21802375
  • Florian Ulrich, Leung-Hang Ma, Robert G. Baker and Jesús Torres-Vázquez. (2011). Neurovascular development in the embryonic zebrafish hindbrain. Developmental Biology 357 (1), 134-151. PMID: 21745463
  • Jesús Torres-Vázquez, Aaron D. Gitler, Sherry D. Fraser, Jason A. Berk, Van N. Pham, Mark C. Fishman, Sarah Childs, Jonathan A. Epstein and Brant M. Weinstein. (2004). Semaphorin-Plexin signaling guides patterning of the developing vasculature. Developmental Cell 7(1), 117-123. PMID: 15239959

Click here to see all publications for Dr. Torres-Vazquez